Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 7/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960083 | 0.80 | ADRA2A (0.61) | ADRA2AADRA2BHTR2ACHRM2CHRM3 | |
| SCHEMBL29140051 | 0.80 | ADRA2A (0.61) | ADRA2AADRA2BHTR2ACHRM2CHRM3 | |
| SCHEMBL8960049 | 0.80 | ADRA2A (0.61) | ADRA2AADRA2BHTR2ACHRM2CHRM3 | |
| SCHEMBL8960071 | 0.79 | ADRA2A (0.56) | ADRA2AADRA2BHTR2ACHRM2CHRM3 | |
| SCHEMBL10354315 | 0.79 | HTR2C (0.42) | ADRA2AADRA2BHTR2AHTR2CHTR2B | |
| SCHEMBL4789087 | 0.79 | ADRA2A (0.59) | ADRA2AADRA2BHTR2ACHRM2CHRM3 | |
| SCHEMBL14904833 | 0.78 | ADRA2A (0.54) | ADRA2AADRA2BHTR2ACHRM2CHRM3 | |
| Bromide SCHEMBL10354107 | 0.78 | HTR2C (0.41) | ADRA2AADRA2BHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL9252509 | 0.78 | ADRA2A (0.58) | ADRA2AADRA2BHTR2ACHRM2CHRM3 | |
| SCHEMBL29140044 | 0.77 | ADRA2A (0.57) | ADRA2AADRA2BHTR2ACHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-0691956-A1 | 3-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVES AS SEDATIVES | LABORATOIRE L. LAFON (FR) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022827-A1 | 3-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVES AS SEDATIVES | LABORATOIRE L. LAFON (FR) | 1994-10-13 | — | — | WO | disclosed |