Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960030 | 0.80 | ALDH1A1 (0.43) | HCAR1ALDH1A1HPGDHIF1AMEN1 | |
| SCHEMBL8960070 | 0.78 | MAPT (0.40) | ALDH1A1TDP1CYP3A4HPGDMEN1 | |
| SCHEMBL8960124 | 0.76 | ESR2 (0.54) | HCAR1POLBESR1ESR2 | |
| SCHEMBL8960266 | 0.76 | ALDH1A1 (0.37) | HCAR1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL9340421 | 0.75 | CYP3A4 (0.52) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL8960188 | 0.74 | HCAR1 (0.36) | HCAR1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL27599008 | 0.71 | ALDH1A1 (0.38) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL9339513 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL9598659 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL8960181 | 0.67 | NR3C2 (0.39) | MEN1KMT2APOLBMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532208-A | HERBICIDES | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5366955-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0568041-A1 | Pyrimidone derivatives and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-03 | — | — | EP | disclosed |