Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.54 |
| ▸ | ESR1 | P03372 | 6/20 | 0.54 |
| ▸ | HCAR1 | Q9BXC0 | 8/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960285 | 0.85 | ESR1 (0.38) | ESR2ESR1HCAR1GRM5GRM1 | |
| SCHEMBL8960163 | 0.76 | HCAR1 (0.37) | ESR2ESR1HCAR1POLB | |
| SCHEMBL8960193 | 0.71 | HCAR1 (0.42) | ESR2ESR1HCAR1GRM5GRM1 | |
| SCHEMBL9343928 | 0.70 | ACHE (0.36) | — | |
| SCHEMBL14176452 | 0.70 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL8960181 | 0.69 | NR3C2 (0.39) | POLB | |
| SCHEMBL8960197 | 0.68 | MAPK11 (0.40) | ESR2ESR1HCAR1GRM5GRM1 | |
| SCHEMBL9599435 | 0.66 | ESR1 (0.43) | ESR2ESR1CAPN1 | |
| SCHEMBL8960539 | 0.65 | EGFR (0.31) | — | |
| SCHEMBL8279156 | 0.65 | ESR1 (0.46) | ESR2ESR1GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532208-A | HERBICIDES | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5366955-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0568041-A1 | Pyrimidone derivatives and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-03 | — | — | EP | disclosed |