Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960197 | 0.83 | MAPK11 (0.40) | HCAR1GLAL3MBTL1ESR1ESR2 | |
| SCHEMBL8960198 | 0.74 | GLA (0.46) | GLAL3MBTL1MAPK11MAPK14GRM5 | |
| SCHEMBL8960285 | 0.71 | ESR1 (0.38) | HCAR1ESR1ESR2CYP17A1GRM5 | |
| SCHEMBL10027269 | 0.69 | ESR1 (0.46) | GLAL3MBTL1ESR1ESR2CYP17A1 | |
| SCHEMBL9723046 | 0.69 | GABRB3 (0.39) | GABRG2GABRB3GABRA5KDM5B | |
| SCHEMBL9412140 | 0.68 | GRM5 (0.42) | HCAR1GLAL3MBTL1ESR1ESR2 | |
| SCHEMBL8960030 | 0.68 | ALDH1A1 (0.43) | HCAR1L3MBTL1ESR1ESR2LMNA | |
| SCHEMBL9581673 | 0.68 | GAA (0.32) | ESR2KDM5B | |
| SCHEMBL9592278 | 0.68 | KDM5B (0.32) | KDM5B | |
| SCHEMBL10027242 | 0.67 | ESR2 (0.41) | HCAR1GLAL3MBTL1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532208-A | HERBICIDES | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5366955-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0568041-A1 | Pyrimidone derivatives and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-03 | — | — | EP | disclosed |