Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 9/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960124 | 0.85 | ESR2 (0.54) | ESR1ESR2HCAR1GRM1GRM5 | |
| SCHEMBL8960163 | 0.72 | HCAR1 (0.37) | ESR1ESR2HCAR1MAPTPOLB | |
| SCHEMBL8960193 | 0.71 | HCAR1 (0.42) | ESR1ESR2HCAR1GRM1GRM5 | |
| SCHEMBL9343928 | 0.70 | ACHE (0.36) | LMNA | |
| SCHEMBL8960181 | 0.69 | NR3C2 (0.39) | MAPTTP53POLB | |
| SCHEMBL9598055 | 0.66 | SMN1; SMN2 (0.41) | MAT2AMAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1670483 | 0.65 | CRACR2A (0.39) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11783075 | 0.65 | ALDH1A1 (0.41) | MAPTPOLBALDH1A1LMNA | |
| SCHEMBL20603901 | 0.64 | FGFR1 (0.51) | MAPTPOLBALDH1A1LMNAMAPK1 | |
| SCHEMBL9340421 | 0.63 | CYP3A4 (0.52) | MAPTSMN1; SMN2POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532208-A | HERBICIDES | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5366955-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0568041-A1 | Pyrimidone derivatives and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-03 | — | — | EP | disclosed |