SCHEMBL8960195

SCHEMBL8960195

[O]S(=O)(=O)c1cccc(I)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
LMNA P02545 2/20 0.37
PMP22 Q01453 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA12 O43570 3/20 0.37
CA9 Q16790 3/20 0.37
FAAH O00519 1/20 0.36
MGLL Q99685 1/20 0.36
CA4 P22748 1/20 0.35
CA14 Q9ULX7 1/20 0.35
HTR6 P50406 4/20 0.35
HTR2C P28335 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HTR1A P08908 1/20 0.33
HTR7 P34969 1/20 0.33
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3677379 0.83 LMNA (0.54) CA1CA2LMNAPMP22SMN1; SMN2
SCHEMBL30084552 0.83 LMNA (0.54) CA1CA2LMNAPMP22SMN1; SMN2
SCHEMBL3371316 0.79 ALDH1A1 (0.57) CA1CA2LMNAPMP22SMN1; SMN2
SCHEMBL3919478 0.79 CA2 (0.70) CA1CA2LMNACA12CA9
SCHEMBL19122490 0.79 CA2 (0.39) CA1CA2LMNAPMP22SMN1; SMN2
SCHEMBL486222 0.79 ALDH1A1 (0.52) CA1CA2LMNAPMP22SMN1; SMN2
SCHEMBL30628286 0.79 ALDH1A1 (0.42) CA1CA2SMN1; SMN2ALDH1A1HSD17B10
SCHEMBL3667501 0.79 ALDH1A1 (0.42) CA1CA2SMN1; SMN2ALDH1A1HSD17B10
Zinc Ion SCHEMBL6916857 0.77 LMNA (0.42) CA1CA2LMNAPMP22SMN1; SMN2
SCHEMBL6917698 0.77 ALDH1A1 (0.55) CA1CA2LMNAPMP22SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112930352-B Silylamine compounds and latent curing agents containing the same 广荣化学株式会社 2024-02-13 CN disclosed
US-20220119583-A1 SILYLAMINE COMPOUND AND LATENT CURING AGENT COMPRISING SAID SILYLAMINE COMPOUND KOEI CHEMICAL COMPANY, LIMITED (JP) 2022-04-21 US disclosed
EP-3875461-A1 SILYLAMINE COMPOUND AND LATENT CURING AGENT COMPRISING SAID SILYLAMINE COMPOUND Koei Chemical Company, Limited (JP) 2021-09-08 EP disclosed
CN-112930352-A Silylamine compound and latent curing agent containing the same 广荣化学株式会社 2021-06-08 CN disclosed
US-5585373-A STABILITY, LOWER TOXICITY TAIHO PHARMACEUTICAL CO., LTD (JP) 1996-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220119583-A1 SILYLAMINE COMPOUND AND LATENT CURING AGENT COMPRISING SAID SILYLAMINE COMPOUND CDKN1A, SIRT2, H1-4 CA1 953/4885CA2 994/4885LMNA 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.