SCHEMBL3667501

SCHEMBL3667501

CS(=O)(=O)c1cccc(I)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
MET P08581 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
LOX P28300 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
GAA P10253 2/20 0.39
HSD17B10 Q99714 1/20 0.39
DRD2 P14416 1/20 0.39
ENPP2 Q13822 2/20 0.39
G6PD P11413 1/20 0.38
IDE P14735 1/20 0.38
KIF11 P52732 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30628286 1.00 ALDH1A1 (0.42) ALDH1A1METSMN1; SMN2LOXLOXL2
SCHEMBL1272809 0.83 NR1H2 (0.48)
SCHEMBL10051059 0.83 CA1 (0.55) ALDH1A1METSMN1; SMN2LOXLOXL2
SCHEMBL30084552 0.81 LMNA (0.54) ALDH1A1SMN1; SMN2CA1CA2GAA
SCHEMBL3677379 0.81 LMNA (0.54) ALDH1A1SMN1; SMN2CA1CA2GAA
SCHEMBL8960195 0.79 CA1 (0.41) ALDH1A1SMN1; SMN2CA1CA2HSD17B10
SCHEMBL22619100 0.78 PSIP1 (0.56) ALDH1A1SMN1; SMN2CA1CA2GAA
SCHEMBL18948539 0.77 CA1 (0.44) ALDH1A1METSMN1; SMN2LOXLOXL2
SCHEMBL3919478 0.77 CA2 (0.70) CA1CA2
SCHEMBL19122490 0.77 CA2 (0.39) ALDH1A1SMN1; SMN2CA1CA2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250233-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE PRILENIA NEUROTHERAPEUTICS LTD. (IL) 2025-08-07 US disclosed
EP-4519246-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE Prilenia Neurotherapeutics Ltd. (IL) 2025-03-12 EP disclosed
WO-2023214412-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE PRILENIA NEUROTHERAPEUTICS LTD. (IL) 2023-11-09 WO disclosed
CN-111170991-B Antiproliferative compounds and methods of synthesis thereof 细胞基因公司 2023-10-31 CN disclosed
EP-3594211-B1 ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF CELGENE CORP (US) 2023-10-25 EP disclosed
US-20220387413-A1 ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF CELGENE CORP (US) 2022-12-08 US disclosed
US-11241423-B2 Antiproliferative compounds and methods of use thereof CELGENE CORPORATION (US) 2022-02-08 US disclosed
US-11136337-B2 Pyrazole- and indazole-substituted oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2021-10-05 US disclosed
US-20210040113-A1 PYRAZOLE- AND INDAZOLE- SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2021-02-11 US disclosed
EP-3733670-A1 TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF Mediconns (Shanghai) Biopharmaceutical Co., Ltd (CN) 2020-11-04 EP disclosed
US-20130261317-A1 METHODS FOR PREPARING SYNTHETIC BILE ACIDS AND COMPOSITIONS COMPRISING THE SAME KYTHERA BIOPHARMACEUTICALS, INC. (US) 2013-10-03 US disclosed
EP-2237779-A1 BENZOTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND METHODS OF USE Abbott Laboratories (US) 2010-10-13 EP disclosed
WO-2009085945-A1 BENZOTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND METHODS OF USE ABBOTT LABORATORIES (US) 2009-07-09 WO disclosed
WO-2007050348-A2 POTASSIUM CHANNEL INHIBITORS MERCK & CO., INC. (US) 2007-05-03 WO disclosed
CN-1028521-C Therapeutic agents BOOTS CO PLC (GB) 1995-05-24 CN disclosed
EP-0536151-B1 ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM BOOTS CO PLC (GB) 1994-09-14 EP disclosed
US-5302720-A Biphenyl-substituted guanidine derivatives useful as hypoglycaemic agents THE BOOTS COMPANY (GB) 1994-04-12 US disclosed
CN-1072173-A Therapeutical agent BOOTS CO PLC (GB) 1993-05-19 CN disclosed
EP-0536151-A1 ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. BOOTS CO PLC (GB) 1993-04-14 EP disclosed
WO-1992000273-A1 ORTHOSUBSTITUTED BIPHENYL AMIDINE AND BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM THE BOOTS COMPANY PLC (GB) 1992-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130261317-A1 METHODS FOR PREPARING SYNTHETIC BILE ACIDS AND COMPOSITIONS COMPRISING THE SAME HSD17B11, DHCR7, CYP46A1 ALDH1A1 1917/4885MET 2153/4885SMN1; SMN2 4372/4885
US-20220387413-A1 ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF MCL1, MKI67, BAX ALDH1A1 247/4885MET 1414/4885SMN1; SMN2 289/4885
US-11241423-B2 Antiproliferative compounds and methods of use thereof MCL1, MKI67, BAX ALDH1A1 247/4885MET 1414/4885SMN1; SMN2 289/4885
US-20250250233-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE QDPR, MAOB, DRD2 ALDH1A1 1588/4885MET 4767/4885SMN1; SMN2 2252/4885
US-20210040113-A1 PYRAZOLE- AND INDAZOLE- SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS GIPR, GPR119, MBOAT4 ALDH1A1 347/4885MET 2368/4885SMN1; SMN2 4544/4885
US-11136337-B2 Pyrazole- and indazole-substituted oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors GIPR, GPR119, MBOAT4 ALDH1A1 347/4885MET 2368/4885SMN1; SMN2 4544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.