Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797138 | 0.81 | HTR6 (0.56) | HTR6KDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL3153616 | 0.76 | HTR6 (0.49) | HTR6POLBKDM4EALDH1A1TUBB4A | |
| SCHEMBL31561597 | 0.75 | CA2 (0.62) | HTR6KDM4EALDH1A1CA2CA12 | |
| SCHEMBL3237494 | 0.75 | CA2 (0.62) | HTR6KDM4EALDH1A1CA2CA12 | |
| SCHEMBL18341923 | 0.74 | SRD5A2 (0.60) | HTR6POLBTUBB4ATUBBTUBA3C | |
| SCHEMBL3326633 | 0.73 | HTR6 (1.00) | HTR6KDM4EALDH1A1 | |
| SCHEMBL4679343 | 0.73 | HTR6 (0.60) | HTR6 | |
| SCHEMBL4675283 | 0.72 | HTR6 (0.76) | HTR6POLB | |
| SCHEMBL30543985 | 0.72 | HTR6 (0.47) | HTR6POLBTUBB4ATUBBTUBA3C | |
| SCHEMBL4263897 | 0.72 | CA2 (0.40) | HTR6POLBGAAGFERKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567827-A | 4-Hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1996-10-22 | — | — | US | disclosed |
| US-5508431-A | 4-hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1996-04-16 | — | — | US | disclosed |
| US-5401855-A | 4-hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1995-03-28 | — | — | US | disclosed |