Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.38 |
| ▸ | SDHB | P21912 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28406247 | 0.87 | SDHB (0.31) | PSIP1SDHB | |
| SCHEMBL11373268 | 0.77 | ALDH1A1 (0.38) | PSIP1SDHBRIPK1KDM4ETP53 | |
| SCHEMBL10354234 | 0.74 | LMNA (0.36) | RIPK1TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL28384733 | 0.72 | CA12 (0.35) | PSIP1KDM4EALPLTP53SMN1; SMN2 | |
| SCHEMBL10727966 | 0.71 | COMT (0.43) | PSIP1GAARIPK1KDM4ETP53 | |
| SCHEMBL11109953 | 0.71 | HTT (0.38) | SDHBTP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL11319484 | 0.69 | ALDH1A1 (0.40) | GAAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5609765 | 0.68 | PSIP1 (0.34) | PSIP1GAAMAPTKMT2A | |
| SCHEMBL16608697 | 0.67 | MAPT (0.35) | PSIP1SDHBGAARIPK1KDM4E | |
| SCHEMBL10872794 | 0.67 | NPSR1 (0.44) | PSIP1TP53MAPTTHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694588-A1 | Triphendioxazine reactive dyes, preparation and use thereof | BAYER AG (DE) | 1996-01-31 | — | — | EP | disclosed |
| US-4912244-A | Vinylsulfonylalkylamino-alkylamines as intermediates for the preparation of fiber-reactive dyes | CIBA-GEIGY CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| US-4782140-A | Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge | CIBA-GIEGY CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |
| US-4754023-A | Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |