SCHEMBL8961274

SCHEMBL8961274

CC(C)c1cc(C(C)(C)C)[c]c(C(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
FABP3 P05413 2/20 0.31
FABP4 P15090 2/20 0.31
FABP5 Q01469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3691761 0.87 CYP1A2 (0.31) CYP1A2CYP2D6
SCHEMBL8961289 0.78 USP2 (0.35)
SCHEMBL1777259 0.73 LMNA (0.33)
SCHEMBL11567002 0.72 TP53 (0.38) CYP2D6
SCHEMBL150439 0.70 GABRA1 (0.43) GABRA1GABRB2
SCHEMBL377542 0.69 GABRA1 (0.48) CYP1A2CYP2D6GABRA1GABRB2FABP3
SCHEMBL11707700 0.69 TSHR (0.37)
SCHEMBL7722741 0.69
SCHEMBL7085860 0.69 GABRA1 (0.42) CYP1A2CYP2D6GABRA1GABRB2FABP3
SCHEMBL224456 0.69 GABRA1 (0.48) CYP1A2GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1062540-A Organic phosphites suitable as stabilizers and polymer compositions containing them HIMONT INC (US) 1992-07-08 CN claimed
EP-0487036-B1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC (US) 1996-02-07 EP disclosed
US-5326801-A Photoresistance, heat resistance, oxidation resistance HIMONT INCORPORATED (US) 1994-07-05 US disclosed
US-5162548-A ORGANIC PHOSPHITES SUITABLE AS STABILIZERS FOR POLYMERS HIMONT INCORPORATED (US) 1992-11-10 US disclosed
CN-1062540-A Organic phosphites suitable as stabilizers and polymer compositions containing them HIMONT INC (US) 1992-07-08 CN disclosed
EP-0487036-A1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC. (US) 1992-05-27 EP disclosed