SCHEMBL8961289

SCHEMBL8961289

CCC(C)c1cc(C(C)(C)C)[c]c(C(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
RORC P51449 1/20 0.34
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4456298 0.87 USP2 (0.31) USP2ALDH1A1GAAPKMHPGD
SCHEMBL8973438 0.81
SCHEMBL8961274 0.78 CYP1A2 (0.34)
SCHEMBL31491205 0.74 GABRA1 (0.41) USP2ALDH1A1GAAPKMHPGD
SCHEMBL11686432 0.74 ALDH1A1 (0.46) USP2ALDH1A1GAAPKMHPGD
SCHEMBL11567002 0.73 TP53 (0.38) ALOX15
SCHEMBL15067244 0.73
SCHEMBL145537 0.71 ALDH1A1 (0.38) USP2ALDH1A1GAAPKMHPGD
SCHEMBL13397821 0.71 HMGCR (0.39) USP2ALDH1A1GAAPKMHPGD
SCHEMBL144821 0.69 CA2 (0.50) USP2ALDH1A1GAAPKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487036-B1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC (US) 1996-02-07 EP claimed
US-5162548-A ORGANIC PHOSPHITES SUITABLE AS STABILIZERS FOR POLYMERS HIMONT INCORPORATED (US) 1992-11-10 US claimed
EP-0487036-A1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC. (US) 1992-05-27 EP claimed
EP-0487036-B1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC (US) 1996-02-07 EP disclosed
US-5326801-A Photoresistance, heat resistance, oxidation resistance HIMONT INCORPORATED (US) 1994-07-05 US disclosed
US-5162548-A ORGANIC PHOSPHITES SUITABLE AS STABILIZERS FOR POLYMERS HIMONT INCORPORATED (US) 1992-11-10 US disclosed
EP-0487036-A1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC. (US) 1992-05-27 EP disclosed