SCHEMBL8961299

SCHEMBL8961299

CCCc1cc(C(C)(C)C)[c]c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
CYP3A4 P08684 1/20 0.30
PTGS2 P35354 1/20 0.30
LPL P06858 1/20 0.30
LIPG Q9Y5X9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8961112 0.89 HPGD (0.45) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL1056583 0.84 PTGS2 (0.50) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL284609 0.81 HSPA5 (0.39) PTGS2
SCHEMBL15066983 0.77 PTGS2 (0.44) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL1777273 0.75 CNR1 (0.37) CNR1CNR2LPLLIPG
SCHEMBL15067850 0.75 PTGS2 (0.46) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL15067499 0.75 PTGS2 (0.46) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL15067413 0.75 PTGS2 (0.46) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL27439090 0.74 NOS1 (0.31)
SCHEMBL2821369 0.74 ACHE (0.39) KMT2AMAPK1NPSR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487036-B1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC (US) 1996-02-07 EP claimed
US-5162548-A ORGANIC PHOSPHITES SUITABLE AS STABILIZERS FOR POLYMERS HIMONT INCORPORATED (US) 1992-11-10 US claimed
EP-0487036-A1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC. (US) 1992-05-27 EP claimed
EP-0487036-B1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC (US) 1996-02-07 EP disclosed
US-5326801-A Photoresistance, heat resistance, oxidation resistance HIMONT INCORPORATED (US) 1994-07-05 US disclosed
US-5162548-A ORGANIC PHOSPHITES SUITABLE AS STABILIZERS FOR POLYMERS HIMONT INCORPORATED (US) 1992-11-10 US disclosed
EP-0487036-A1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC. (US) 1992-05-27 EP disclosed