Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067850 | 1.00 | PTGS2 (0.46) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL15067499 | 1.00 | PTGS2 (0.46) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL15066983 | 0.98 | PTGS2 (0.44) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL1056583 | 0.91 | PTGS2 (0.50) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL8961112 | 0.85 | HPGD (0.45) | PTGS2CYP3A4GPR84ALDH1A1HSD17B10 | |
| SCHEMBL3693245 | 0.85 | PTGS2 (0.44) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL7949508 | 0.77 | HSPA5 (0.36) | PTGS2 | |
| SCHEMBL8961299 | 0.75 | GAA (0.33) | PTGS2CYP3A4NPC1HPGDMAPK1 | |
| SCHEMBL9836104 | 0.74 | PTGS2 (0.55) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL9306772 | 0.74 | PTGS2 (0.55) | PTGS2CYP3A4GPR84ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797939-B1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2018-10-31 | — | — | EP | claimed |
| US-9108988-B2 | Method of purifying organic diphosphite compounds | BASF SE (DE) | 2015-08-18 | — | — | US | claimed |
| EP-2797939-A1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2014-11-05 | — | — | EP | claimed |
| US-20130225849-A1 | METHOD OF PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2013-08-29 | — | — | US | claimed |
| WO-2013098368-A1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2013-07-04 | — | — | WO | claimed |
| CN-108026062-B | Process for the hydroformylation of 2-substituted butadienes and process for the production of secondary products thereof, in particular ambrox | 巴斯夫欧洲公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-3319951-B1 | METHOD FOR THE HYDROFORMYLATION OF 2-SUBSTITUTED BUTADIENES AND FOR THE PREPARATION OF PRODUCTS DERIVED FROM SAME, PARTICULARLY FROM AMBROX | BASF SE (DE) | 2021-09-08 | — | — | EP | disclosed |
| US-10315975-B2 | Method for the hydroformylation of 2-substituted butadienes and the production of secondary products thereof, especially ambrox | BASF SE (DE) | 2019-06-11 | — | — | US | disclosed |
| EP-2797939-B1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2018-10-31 | — | — | EP | disclosed |
| US-20180273458-A1 | METHOD FOR THE HYDROFORMYLATION OF 2-SUBSTITUTED BUTADIENES AND THE PRODUCTION OF SECONDARY PRODUCTS THEREOF, ESPECIALLY AMBROX | RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG (DE) | 2018-09-27 | — | — | US | disclosed |
| EP-3319951-A1 | METHOD FOR THE HYDROFORMYLATION OF 2-SUBSTITUTED BUTADIENES AND THE PRODUCTION OF SECONDARY PRODUCTS THEREOF, ESPECIALLY AMBROX | BASF SE (DE) | 2018-05-16 | — | — | EP | disclosed |
| US-9108988-B2 | Method of purifying organic diphosphite compounds | BASF SE (DE) | 2015-08-18 | — | — | US | disclosed |
| EP-2797939-A1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2014-11-05 | — | — | EP | disclosed |
| US-20130225849-A1 | METHOD OF PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2013-08-29 | — | — | US | disclosed |
| WO-2013098368-A1 | METHOD FOR PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | BASF SE (DE) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10315975-B2 | Method for the hydroformylation of 2-substituted butadienes and the production of secondary products thereof, especially ambrox | ALOX12, ALOX15, ALOX5 | PTGS2 101/4885CYP3A4 357/4885GPR84 2269/4885 |
| US-20130225849-A1 | METHOD OF PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS | DCTPP1, DCPS, PPIP5K2 | PTGS2 1827/4885CYP3A4 427/4885GPR84 4499/4885 |
| US-20180273458-A1 | METHOD FOR THE HYDROFORMYLATION OF 2-SUBSTITUTED BUTADIENES AND THE PRODUCTION OF SECONDARY PRODUCTS THEREOF, ESPECIALLY AMBROX | ALOX12, ALOX15, ALOX5 | PTGS2 101/4885CYP3A4 357/4885GPR84 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.