SCHEMBL8961373

SCHEMBL8961373

N#CNC(=O)c1[c]cccc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.33
MCL1 Q07820 1/20 0.32
PLIN1 O60240 1/20 0.30
LMNA P02545 1/20 0.30
PLIN5 Q00G26 1/20 0.30
ABHD5 Q8WTS1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3764584 0.77 CTSL (0.43) MCL1
SCHEMBL224092 0.76 HDAC8 (0.46) LMNA
SCHEMBL3982156 0.75 GUSB (0.42) MCL1
SCHEMBL4904390 0.75 GAA (0.39) LMNA
SCHEMBL295086 0.75 GAA (0.42)
SCHEMBL483177 0.72 RAB9A (0.49) LMNA
SCHEMBL8961335 0.71 GAA (0.33) LMNA
SCHEMBL11044094 0.71 KMT2A (0.46) LMNA
SCHEMBL8804677 0.71
SCHEMBL143892 0.71 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694053-A1 WATER-SOLUBLE FIBER-REACTIVE DYES, PROCESS FOR PRODUCING THE SAME AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-31 EP disclosed
WO-1994024214-A1 WATER-SOLUBLE FIBER-REACTIVE DYES, PROCESS FOR PRODUCING THE SAME AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-27 WO disclosed