Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.45 |
| ▸ | REN | P00797 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5891423 | 0.86 | FNTA (0.39) | SCN9ARENKMT2A | |
| SCHEMBL8079882 | 0.86 | FNTA (0.39) | SCN9ARENKMT2A | |
| SCHEMBL9437492 | 0.84 | SCN9A (0.44) | SCN9ARENKMT2ACTSD | |
| SCHEMBL8075177 | 0.83 | KDM4E (0.34) | SCN9AREN | |
| SCHEMBL8065171 | 0.82 | SYK (0.35) | SCN9ARENKMT2A | |
| SCHEMBL8075650 | 0.81 | CTRB1 (0.34) | SCN9ARENCTSD | |
| SCHEMBL8075466 | 0.81 | SCN9A (0.33) | SCN9AREN | |
| SCHEMBL8065509 | 0.81 | KMT2A (0.33) | SCN9ARENKMT2A | |
| SCHEMBL8065165 | 0.80 | KMT2A (0.32) | SCN9ARENKMT2A | |
| SCHEMBL7513070 | 0.80 | SCN9A (0.61) | SCN9AREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480893-A | ANTITUMOR | MERCK & CO., INC. (US) | 1996-01-02 | — | — | US | disclosed |