SCHEMBL8961764

SCHEMBL8961764

CCCC1CCC(C2CCC(c3ccc(-c4ccc(-c5ccc(OCC)c(F)c5F)cc4)c(F)c3F)CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 5/20 0.34
ALOX5AP P20292 3/20 0.33
FEN1 P39748 3/20 0.33
FGFR1 P11362 1/20 0.33
FGFR2 P21802 1/20 0.33
GRIN1 Q05586 1/20 0.32
GRIN2B Q13224 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
S1PR1 P21453 8/20 0.32
CYP2C9 P11712 1/20 0.31
S1PR4 O95977 2/20 0.31
S1PR3 Q99500 2/20 0.31
S1PR5 Q9H228 2/20 0.31
S1PR2 O95136 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8934887 0.96 FPR2 (0.35) FPR2ALOX5APFEN1FGFR1FGFR2
SCHEMBL9979235 0.94 FPR2 (0.33) FPR2ALOX5APFEN1FGFR1FGFR2
SCHEMBL8961767 0.93 FPR2 (0.36) FPR2ALOX5APFEN1FFAR4CYP2C9
SCHEMBL8961943 0.92 GAA (0.33) FPR2ALOX5APFEN1FGFR1FGFR2
SCHEMBL12999639 0.92 ALOX5AP (0.32) FPR2ALOX5APFEN1
SCHEMBL8961771 0.92 SCN9A (0.32) FPR2ALOX5APFEN1
SCHEMBL1311026 0.92 CYP2C9 (0.35) CYP2C9
SCHEMBL4400193 0.92 CYP2C9 (0.35) CYP2C9
SCHEMBL17614853 0.92 CYP2C9 (0.35) CYP2C9
SCHEMBL427347 0.92 CYP2C9 (0.35) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
US-20100309402-A1 FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100309402-A1 FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE KIF23, HCN3, FZD7 FPR2 1427/4885ALOX5AP 1414/4885FEN1 4226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.