Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21523260 | 0.89 | SHBG (0.36) | MAPTTDP1GAAMEN1KMT2A | |
| SCHEMBL29945080 | 0.87 | MAPT (0.42) | MAPTTDP1GAAKDM4EMEN1 | |
| SCHEMBL17254861 | 0.84 | MAPT (0.44) | MAPTTDP1GAAKDM4EMEN1 | |
| SCHEMBL8962174 | 0.80 | GAA (0.41) | MAPTTDP1GAAKDM4EMEN1 | |
| SCHEMBL8962199 | 0.79 | TDP1 (0.50) | MAPTTDP1GAAKDM4EMEN1 | |
| SCHEMBL30172544 | 0.77 | CCR4 (0.47) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL9429869 | 0.77 | CCR4 (0.47) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL30798973 | 0.77 | CCR4 (0.47) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL31916 | 0.76 | MAPT (0.47) | MAPTTDP1GAAKDM4EMEN1 | |
| SCHEMBL8962181 | 0.74 | SHBG (0.52) | MAPTTDP1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512950-B1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | disclosed |
| US-5244953-A | Polymers, oxidation and heat resistance | CIBA-GEIGY CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0512950-A1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| US-5160647-A | High temperature lubricants, heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1992-11-03 | — | — | US | disclosed |