Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435078 | 0.88 | ALOX15 (0.48) | ALDH1A1TSHRCA1CA2MMP1 | |
| SCHEMBL347237 | 0.88 | ALOX15 (0.48) | ALDH1A1TSHRCA1CA2MMP1 | |
| SCHEMBL11608183 | 0.84 | SLC16A1 (0.44) | ALDH1A1PBRM1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL29676384 | 0.81 | NPSR1 (0.47) | ALDH1A1TSHRCA1CA2MMP1 | |
| SCHEMBL34677 | 0.81 | NPSR1 (0.47) | ALDH1A1TSHRCA1CA2MMP1 | |
| SCHEMBL28326658 | 0.78 | HTT (0.47) | ALDH1A1TSHRCA1CA2MMP1 | |
| SCHEMBL4915950 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRCA1CA2MMP1 | |
| SCHEMBL11777616 | 0.78 | ALDH1A1 (0.45) | ALDH1A1PBRM1TSHRCA1CA2 | |
| SCHEMBL29443910 | 0.78 | ALOX15 (0.46) | ALDH1A1PBRM1TSHRCA1CA2 | |
| SCHEMBL7899541 | 0.78 | ALOX15 (0.46) | ALDH1A1PBRM1TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |