Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | CDC25A | P30304 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058645 | 0.87 | CDC25B (1.00) | CDC25BHSD17B10CDC25AKDM4EPOLB | |
| SCHEMBL3074652 | 0.87 | CDC25B (1.00) | CDC25BHSD17B10CDC25AKDM4EPOLB | |
| SCHEMBL257674 | 0.87 | ALDH1A1 (0.64) | CDC25BHSD17B10CDC25AKDM4EPOLB | |
| SCHEMBL7118447 | 0.82 | SRD5A2 (0.59) | CDC25BHSD17B10CDC25AKDM4EALDH1A1 | |
| SCHEMBL256745 | 0.82 | CDC25B (0.51) | CDC25BHSD17B10CDC25AKDM4EPOLB | |
| SCHEMBL9178259 | 0.81 | ALDH1A1 (0.61) | CDC25BHSD17B10CDC25AALDH1A1AKR1C3 | |
| SCHEMBL10759830 | 0.81 | CES2 (0.62) | CDC25BHSD17B10KDM4ETDP1ALDH1A1 | |
| SCHEMBL10047111 | 0.81 | CDC25B (0.50) | CDC25BHSD17B10CDC25AKDM4EPOLB | |
| SCHEMBL9487939 | 0.80 | HSD17B14 (0.57) | CDC25BHSD17B10CDC25AKDM4ETDP1 | |
| SCHEMBL1295856 | 0.80 | CDC25B (0.78) | CDC25BHSD17B10CDC25AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |