SCHEMBL8962329

SCHEMBL8962329

Oc1ccc(O)c(-c2cccc3[nH]nnc23)c1-c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
HSD17B1 P14061 1/20 0.35
CYP2B6 P20813 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B2 P37059 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ADORA2A P29274 1/20 0.34
ALOX15 P16050 1/20 0.34
GYS1 P13807 1/20 0.34
BACE1 P56817 2/20 0.33
MGAM O43451 2/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9268433 0.84 MAOA (0.38) CYP3A4ALDH1A1HPGDHSD17B10ALOX15
SCHEMBL80394 0.83 CHEK1 (0.37) CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1
SCHEMBL29359068 0.83 CHEK1 (0.37) CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1
SCHEMBL8962327 0.82 MGAM (0.39) ALDH1A1HPGDBCL2L1HSD17B10ADORA2A
SCHEMBL6897857 0.81 CHEK1 (0.36) CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1
SCHEMBL8836008 0.81 CHEK1 (0.36) CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1
SCHEMBL2037376 0.81 MAOA (0.36) METAP2CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL165334 0.81 METAP2 (0.49) METAP2ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL29669794 0.81 METAP2 (0.49) METAP2ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL719444 0.80 NSD2 (0.41) CYP1A2CYP2C9CYP2C19ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623602-B1 Asymmetrical benzotriazolylphenols FAIRMOUNT CHEM (US) 1996-01-17 EP claimed
EP-0623602-A1 Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL CO., INC. (US) 1994-11-09 EP claimed
US-5360850-A Ultraviolet radiation stabilizers FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-11-01 US claimed
US-5292890-A Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-03-08 US claimed
EP-0623602-B1 Asymmetrical benzotriazolylphenols FAIRMOUNT CHEM (US) 1996-01-17 EP disclosed
EP-0623602-A1 Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL CO., INC. (US) 1994-11-09 EP disclosed
EP-0623602-A1 Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL CO., INC. (US) 1994-11-09 EP disclosed
US-5360850-A Ultraviolet radiation stabilizers FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-11-01 US disclosed
US-5360850-A Ultraviolet radiation stabilizers FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-11-01 US disclosed
US-5292890-A Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-03-08 US disclosed
US-5292890-A Asymmetrical benzotriazolylphenols FAIRMOUNT CHEMICAL COMPANY, INC. (US) 1994-03-08 US disclosed