Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21184203 | 0.90 | LMNA (0.64) | LMNAAPEX1POLBCTDSP1L3MBTL1 | |
| SCHEMBL27669128 | 0.86 | LMNA (0.58) | LMNAAPEX1POLBCTDSP1L3MBTL1 | |
| SCHEMBL1018611 | 0.84 | LMNA (0.61) | LMNAAPEX1POLBALDH1A1KDM4E | |
| SCHEMBL4419627 | 0.84 | ALDH1A1 (0.68) | LMNAPOLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1017780 | 0.84 | LMNA (0.61) | LMNAALDH1A1HSD17B10ENPP2AKR1C3 | |
| SCHEMBL35247 | 0.84 | LMNA (0.66) | LMNAPOLBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL30868512 | 0.84 | ALDH1A1 (0.68) | LMNAPOLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1042597 | 0.84 | LMNA (0.61) | LMNAPOLBCTDSP1ALDH1A1KDM4E | |
| SCHEMBL1397921 | 0.83 | APEX1 (0.67) | LMNAAPEX1POLBCTDSP1L3MBTL1 | |
| SCHEMBL65212 | 0.83 | APEX1 (0.67) | LMNAAPEX1POLBCTDSP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |