Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27891624 | 0.86 | LMNA (0.49) | LMNAALDH1A1AKR1C3AKR1C2MEN1 | |
| SCHEMBL2807317 | 0.86 | APEX1 (0.53) | LMNAALDH1A1RXRBRXRAHSD17B10 | |
| SCHEMBL35247 | 0.85 | LMNA (0.66) | LMNAALDH1A1MAPK1AKR1C3AKR1C2 | |
| SCHEMBL1482128 | 0.85 | LMNA (0.47) | LMNAALDH1A1MEN1KMT2AENPP2 | |
| SCHEMBL3496072 | 0.85 | ALDH1A1 (0.58) | LMNAALDH1A1RXRBRXRAHSD17B10 | |
| SCHEMBL8962352 | 0.84 | LMNA (0.70) | LMNAALDH1A1MAPK1AKR1C3AKR1C2 | |
| SCHEMBL31637076 | 0.83 | RXRB (0.45) | LMNAALDH1A1RXRBRXRAHSD17B10 | |
| SCHEMBL1048077 | 0.83 | CA2 (0.55) | ALDH1A1HSD17B10PHLPP2 | |
| SCHEMBL1279551 | 0.83 | LMNA (0.46) | LMNAALDH1A1RXRBRXRAHSD17B10 | |
| SCHEMBL27462999 | 0.83 | LMNA (0.50) | LMNAALDH1A1AKR1C3AKR1C2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775715-A | High-strength glass fiber reinforced plastic for composite cylindrical shell and preparation method thereof | 新乡学院 | 2025-04-08 | — | — | CN | claimed |
| CN-119775715-A | High-strength glass fiber reinforced plastic for composite cylindrical shell and preparation method thereof | 新乡学院 | 2025-04-08 | — | — | CN | disclosed |
| CN-114206335-B | KCNT1 inhibitors and methods of use | 普拉克西斯精密药物股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| US-20250059220-A1 | SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-02-20 | — | — | US | disclosed |
| US-20240368150-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER | HOFFMANN-LA ROCHE INC. (US) | 2024-11-07 | — | — | US | disclosed |
| EP-4446314-A2 | KCNT1 INHIBITORS AND METHODS OF USE | Praxis Precision Medicines, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| CN-112313209-B | Herbicidal compounds | 先正达农作物保护股份公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-3962479-B1 | KCNT1 INHIBITORS AND METHODS OF USE | PRAXIS PREC MEDICINES INC (US) | 2024-07-24 | — | — | EP | disclosed |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2024-04-11 | — | — | US | disclosed |
| US-20230303487-A1 | PROCESS FOR PREPARATION OF MESOTRIONE AND ITS INTERMEDIATES | RALLIS INDIA LIMITED (IN) | 2023-09-28 | — | — | US | disclosed |
| CN-101072755-A | Pyridyl inhibitors of Hedgehog signaling | GENENTECH INC (US) | 2007-11-14 | — | — | CN | disclosed |
| EP-1789390-A2 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | Genentech, Inc. (US) | 2007-05-30 | — | — | EP | disclosed |
| US-20060063779-A1 | Pyridyl inhibitors of hedgehog signalling | CURIS ROYALTY LLC | 2006-03-23 | — | — | US | disclosed |
| WO-2006028958-A2 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-08-15 | — | — | US | disclosed |
| US-6355633-B1 | CONTRACEPTIVES | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-12 | — | — | US | disclosed |
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |
| US-4990648-A | Process for producing an alkylthiobenzoate | ICI AMERICAS INC. (US) | 1991-02-05 | — | — | US | disclosed |
| WO-1990006915-A1 | PROCESS FOR PRODUCING 2-ALKYL- AND 2-(SUBSTITUTED ALKYL)-4-ALKYLTHIO AND ALKYLSULFONYL-BENZOIC ACIDS AND THEIR DERIVATIVES | ICI AMERICAS INC. (US) | 1990-06-28 | — | — | WO | disclosed |
| US-4925970-A | Process for producing cyclohexadiene thioether | ICI AMERICAS INC., A CORP. OF DE. | 1990-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303487-A1 | PROCESS FOR PREPARATION OF MESOTRIONE AND ITS INTERMEDIATES | COMT, NDUFS3, NDUFS7 | LMNA 4549/4885ALDH1A1 570/4885MAPK1 2739/4885 |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | SHH, GLI1, SMO | LMNA 3718/4885ALDH1A1 2371/4885MAPK1 118/4885 |
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | FSHR, GNRHR, LHCGR | LMNA 3330/4885ALDH1A1 3990/4885MAPK1 1934/4885 |
| US-20240368150-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER | BICRA, BRD4, CNR1 | LMNA 1142/4885ALDH1A1 1572/4885MAPK1 3904/4885 |
| US-20250059220-A1 | SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF | SULT1E1, TPMT, SULT1A1 | LMNA 4754/4885ALDH1A1 211/4885MAPK1 3968/4885 |
| US-20060063779-A1 | Pyridyl inhibitors of hedgehog signalling | SHH, GLI1, SMO | LMNA 3716/4885ALDH1A1 2407/4885MAPK1 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.