Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 6/20 | 0.49 |
| ▸ | THRA | P10827 | 5/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962434 | 1.00 | MAOA (0.51) | MAOAMAOBTHRBTHRAPTPN11 | |
| SCHEMBL8962705 | 0.88 | PTPN11 (0.53) | THRBTHRAPTPN11TP53TSHR | |
| SCHEMBL8962693 | 0.88 | PTPN11 (0.53) | THRBTHRAPTPN11TP53TSHR | |
| SCHEMBL26355067 | 0.86 | MAOA (0.60) | MAOAMAOBTHRBTHRAPTPN11 | |
| SCHEMBL19549621 | 0.86 | MAOA (0.60) | MAOAMAOBTHRBTHRAPTPN11 | |
| SCHEMBL8962432 | 0.82 | THRB (0.53) | MAOAMAOBTHRBTHRAPTPN11 | |
| SCHEMBL16482859 | 0.82 | MAOA (0.54) | MAOAMAOBTHRBTHRAPTPN11 | |
| SCHEMBL5096583 | 0.80 | MAOA (0.52) | MAOAMAOBTHRBTHRAPTPN11 | |
| SCHEMBL16836640 | 0.80 | MAOA (0.62) | MAOAMAOBTHRBTHRAPTPN11 | |
| SCHEMBL22264119 | 0.79 | THRB (0.64) | MAOAMAOBTHRBTHRAPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554706-A | LOW TEMPERATURE LIQUID CRYSTALS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0695770-A1 | COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-02-07 | — | — | EP | disclosed |