Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 5/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19549621 | 0.90 | MAOA (0.60) | MAOAMAOBTHRATHRBPTPN11 | |
| SCHEMBL26355067 | 0.90 | MAOA (0.60) | MAOAMAOBTHRATHRBPTPN11 | |
| SCHEMBL5096611 | 0.88 | PTPN11 (0.54) | THRATHRBPTPN11ALDH1A1L3MBTL1 | |
| SCHEMBL16482859 | 0.86 | MAOA (0.54) | MAOAMAOBTHRATHRBPTPN11 | |
| SCHEMBL4304885 | 0.82 | HDAC3 (0.54) | MAOAMAOBTHRATHRBALDH1A1 | |
| SCHEMBL8962432 | 0.81 | THRB (0.53) | MAOAMAOBTHRATHRBPTPN11 | |
| SCHEMBL27713611 | 0.81 | THRB (0.47) | THRATHRBPTPN11ALDH1A1TP53 | |
| SCHEMBL10430684 | 0.81 | THRA (0.54) | THRATHRBPTPN11TP53TSHR | |
| SCHEMBL16836640 | 0.81 | MAOA (0.62) | MAOAMAOBTHRATHRBPTPN11 | |
| SCHEMBL28519834 | 0.80 | TDP1 (0.51) | MAOAMAOBTHRATHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7416682-B2 | Photochromic liquid crystals | CHI MEI OPTOELECTRONICS CORPORATION (TW) | 2008-08-26 | — | — | US | disclosed |
| EP-1517977-B1 | PHOTOCHROMIC LIQUID CRYSTALS | QINETIQ LTD (GB) | 2006-10-11 | — | — | EP | disclosed |
| US-20050258396-A1 | Potochromic liquid crystals | QINETIQ LIMITED (GB) | 2005-11-24 | — | — | US | disclosed |
| EP-1517977-A1 | PHOTOCHROMIC LIQUID CRYSTALS | Qinetiq Limited (GB) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004003107-A1 | POTOCHROMIC LIQUID CRYSTALS | QINETIQ LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |