Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.53 |
| ▸ | THRA | P10827 | 8/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962697 | 0.88 | PTPN11 (0.54) | THRBTHRAPTPN11TP53TSHR | |
| SCHEMBL19549621 | 0.87 | MAOA (0.60) | THRBTHRAMAOAMAOBPTPN11 | |
| SCHEMBL16482859 | 0.83 | MAOA (0.54) | THRBTHRAMAOAMAOBPTPN11 | |
| SCHEMBL8962430 | 0.82 | MAOA (0.51) | THRBTHRAMAOAMAOBPTPN11 | |
| SCHEMBL8962434 | 0.82 | MAOA (0.51) | THRBTHRAMAOAMAOBPTPN11 | |
| SCHEMBL5096583 | 0.81 | MAOA (0.52) | THRBTHRAMAOAMAOBPTPN11 | |
| SCHEMBL16836640 | 0.81 | MAOA (0.62) | THRBTHRAMAOAMAOBPTPN11 | |
| SCHEMBL4304885 | 0.79 | HDAC3 (0.54) | THRBTHRAMAOAMAOBCNR1 | |
| SCHEMBL8085882 | 0.79 | MAOA (0.60) | THRBTHRAMAOAMAOBPTPN11 | |
| SCHEMBL22439018 | 0.79 | PTPN11 (0.55) | THRBTHRAMAOAMAOBPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554706-A | LOW TEMPERATURE LIQUID CRYSTALS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0695770-A1 | COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-02-07 | — | — | EP | disclosed |