SCHEMBL8962433

SCHEMBL8962433

C=C(C)COCCC[Si](C)(Cl)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR174 Q9BXC1 1/20 0.31
NR1I2 O75469 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
DRD1 P21728 1/20 0.31
TBXA2R P21731 1/20 0.31
AGTR1 P30556 1/20 0.31
PTGIR P43119 1/20 0.31
PDE4D Q08499 1/20 0.31
PTGDR Q13258 1/20 0.31
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
ALOX12 P18054 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715812 0.87 GPR174 (0.32) GPR174NR1I2ADORA3DRD1TBXA2R
SCHEMBL4807090 0.87 GPR174 (0.32) GPR174NR1I2ADORA3DRD1TBXA2R
SCHEMBL17287251 0.83 GPR174 (0.33) GPR174NR1I2ADORA3DRD1TBXA2R
SCHEMBL393257 0.80 GPR174 (0.30) GPR174
SCHEMBL3517110 0.79 GPR174 (0.31) GPR174MEN1KMT2ALMNAMAPT
SCHEMBL394444 0.79
SCHEMBL2345675 0.77 SMN1; SMN2 (0.32) GPR174
SCHEMBL6115807 0.77 GPR174 (0.30) GPR174
SCHEMBL8962436 0.77 TDP1 (0.46) MAPT
SCHEMBL4444485 0.77 L3MBTL1 (0.35) GPR174MEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5554706-A LOW TEMPERATURE LIQUID CRYSTALS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed
US-5098981-A POLYORGANOSILOXANE CHISSO CORPORATION (JP) 1992-03-24 US disclosed