SCHEMBL4444485

SCHEMBL4444485

C=C(C)COCCC[Si](C)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
RECQL P46063 2/20 0.35
TSHR P16473 1/20 0.35
GPR174 Q9BXC1 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
PAX8 Q06710 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
KCNA3 P22001 1/20 0.32
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
KDM4E B2RXH2 1/20 0.30
USP2 O75604 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL852399 0.88 L3MBTL1 (0.35) L3MBTL1RECQLTSHRGPR174MEN1
SCHEMBL1857566 0.87 L3MBTL1 (0.36) L3MBTL1RECQLTSHRGPR174MEN1
SCHEMBL8899639 0.87 L3MBTL1 (0.36) L3MBTL1RECQLTSHRGPR174MEN1
SCHEMBL2167792 0.83 RECQL (0.36) L3MBTL1RECQLTSHRGPR174MEN1
SCHEMBL2166943 0.83 RECQL (0.36) L3MBTL1RECQLTSHRGPR174MEN1
SCHEMBL230550 0.77 TDP1 (0.49) L3MBTL1RECQLTSHRMAPTMTNR1A
SCHEMBL17287251 0.77 GPR174 (0.33) L3MBTL1RECQLTSHRGPR174MEN1
SCHEMBL705384 0.77 KCNA3 (0.41) L3MBTL1RECQLTSHRLMNAKCNA3
SCHEMBL704371 0.77 KCNA3 (0.41) L3MBTL1RECQLTSHRLMNAKCNA3
SCHEMBL8962433 0.77 GPR174 (0.31) GPR174MEN1KMT2AMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593234-B2 Rubber composition having intramolecular double bond THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-03-14 US disclosed
US-20150329708-A1 RUBBER COMPOSITION HAVING INTRAMOLECULAR DOUBLE BOND THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-11-19 US disclosed
US-8557926-B2 Method for producing modified polymer THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-10-15 US disclosed
US-20130053517-A1 METHOD FOR PRODUCING MODIFIED POLYMER YOKOHAMA RUBBER CO., LTD. (JP) 2013-02-28 US disclosed
EP-1958980-B1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR CORP (JP) 2012-10-31 EP disclosed
US-20090270525-A1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR CORPORATION (JP) 2009-10-29 US disclosed
EP-1958980-A1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR Corporation (JP) 2008-08-20 EP disclosed
EP-1245585-B1 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORP (JP) 2008-05-21 EP disclosed
US-6838538-B2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2005-01-04 US disclosed
US-20030100683-A1 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2003-05-29 US disclosed
EP-1245585-A2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR Corporation (JP) 2002-10-02 EP disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US disclosed