SCHEMBL8962466

SCHEMBL8962466

C=C(C#N)C(=O)OCC[Si](C)(C)Cl

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.55
TSHR P16473 1/20 0.55
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962614 0.90 TSHR (0.51) ALDH1A1TSHR
SCHEMBL604549 0.86 TSHR (0.58) ALDH1A1TSHRTHRB
SCHEMBL602482 0.79 TSHR (0.55) ALDH1A1TSHRTHRB
SCHEMBL5878853 0.79 ALDH1A1 (0.55) ALDH1A1TSHRTHRB
SCHEMBL4579700 0.79 TSHR (0.68) ALDH1A1TSHRTHRB
SCHEMBL8962437 0.78 THRB (0.33) TSHRTHRB
SCHEMBL6512429 0.78 THRB (0.50) ALDH1A1TSHRTHRB
SCHEMBL11809888 0.77 TSHR (0.56) ALDH1A1TSHRTHRB
SCHEMBL8962659 0.77 THRB (0.32) TSHRTHRB
SCHEMBL167355 0.76 TSHR (0.70) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed