SCHEMBL896315

SCHEMBL896315

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nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
PGD P52209 2/20 0.32
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19514767 1.00 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL28352023 1.00 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL16634764 0.95 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL20603238 0.89 PGD (0.33) PGDPTPN1
SCHEMBL16038475 0.89 PGD (0.33) PGDPTPN1
SCHEMBL7076428 0.88 PDE4A (0.32) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL37329 0.84 PGD (0.36) LMNAL3MBTL1PDE4APGD
SCHEMBL4959396 0.84 PGD (0.36) LMNAL3MBTL1PDE4APGD
SCHEMBL9736395 0.84 PGD (0.36) LMNAL3MBTL1PDE4APGD
Fructose SCHEMBL769239 0.83 PGD (0.34) PDE4APGDCYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4627351-A1 METHODS FOR DETECTING METABOLIC MARKERS Cedars-Sinai Medical Center (US) 2025-10-08 EP disclosed
US-20250283891-A1 METHODS FOR DETECTING METABOLIC MARKERS CEDARS SINAI MEDICAL CENTER (US) 2025-09-11 US disclosed
CN-118525097-A Novel promoter variants for constitutive expression and uses thereof 大象株式会社 2024-08-20 CN disclosed
WO-2024118850-A1 METHODS FOR DETECTING METABOLIC MARKERS CEDARS-SINAI MEDICAL CENTER (US) 2024-06-06 WO disclosed
CN-117016703-A Lipid-lowering antioxidant fruit and vegetable beverage and preparation method thereof 杭州天曲生物技术有限公司 2023-11-10 CN disclosed
US-20220071880-A1 METHODS FOR TREATING CUTANEOUS AGING Applied Therapeutics, Inc. (US) 2022-03-10 US disclosed
EP-3924060-A1 METHODS FOR TREATING CUTANEOUS AGING Applied Therapeutics Inc. (US) 2021-12-22 EP disclosed
WO-2020167937-A1 METHODS FOR TREATING CUTANEOUS AGING Applied Therapeutics, Inc. (US) 2020-08-20 WO disclosed
EP-1021175-B1 COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS FOX CHASE CANCER CT (US) 2015-04-08 EP disclosed
EP-1311847-B1 Quantitative analysis of hexose-monophosphates from biological samples STATENS SERUMINSTITUT (DK) 2015-01-14 EP disclosed
EP-1126856-A1 COMPOUNDS AND THEIR THERAPEUTIC USE WITH DIABETIC COMPLICATIONS FOX CHASE CANCER CENTER (US) 2001-08-29 EP disclosed
EP-1085885-A2 METHOD FOR ASSESSING A DIABETIC'S RISK OF EXPERIENCING A DIABETES-ASSOCIATED PATHOLOGIC CONDITION FOX CHASE CANCER CENTER (US) 2001-03-28 EP disclosed
WO-2000024405-A9 COMPOUNDS AND THEIR THERAPEUTIC USE WITH DIABETIC COMPLICATIONS FOX CHASE CANCER CENTER (US) 2000-10-19 WO disclosed
EP-1021175-A1 COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS FOX CHASE CANCER CENTER (US) 2000-07-26 EP disclosed
WO-2000024405-A1 COMPOUNDS AND THEIR THERAPEUTIC USE WITH DIABETIC COMPLICATIONS FOX CHASE CANCER CENTER (US) 2000-05-04 WO disclosed
US-6004958-A ADMINISTERING FRUCTOSE-LYSINE-3-PHOSPHATE KINASE INHIBITOR; INHIBITING DEOXYGLUCOSONE BY-PRODUCT FORMATION FOX CHASE CANCER CENTER (US) 1999-12-21 US disclosed
WO-1999064561-A2 METHOD FOR ASSESSING A DIABETIC'S RISK OF EXPERIENCING A DIABETES-ASSOCIATED PATHOLOGIC CONDITION FOX CHASE CANCER CENTER (US) 1999-12-16 WO disclosed
WO-1998033492-A1 COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS FOX CHASE CANCER CENTER (US) 1998-08-06 WO disclosed
US-5231031-A Metabolites FOX CHASE CANCER CENTER (US) 1993-07-27 US disclosed
US-5231031-A Metabolites FOX CHASE CANCER CENTER (US) 1993-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220071880-A1 METHODS FOR TREATING CUTANEOUS AGING GLA, ADH1B, ALDH2 LMNA 1138/4885L3MBTL1 3548/4885PDE4A 326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.