Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407911 | 0.75 | — | — | |
| SCHEMBL6746018 | 0.72 | ALDH1A1 (0.35) | ALDH1A1GAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL1270480 | 0.72 | ALDH1A1 (0.54) | ALDH1A1ALOX15CPB1MEN1KMT2A | |
| SCHEMBL5576207 | 0.71 | PKM (0.40) | ALDH1A1ALOX15GAAL3MBTL1MEN1 | |
| SCHEMBL9479020 | 0.70 | MT-CO2 (0.50) | ALDH1A1GAASMN1; SMN2POLBKDM4E | |
| SCHEMBL31530628 | 0.67 | GSK3B (0.40) | — | |
| SCHEMBL21575557 | 0.67 | MME (0.31) | MAPT | |
| Phthalic Acid SCHEMBL3700659 | 0.67 | ALDH1A1 (0.78) | ALDH1A1ALOX15SMN1; SMN2TSHRPOLB | |
| SCHEMBL21167217 | 0.67 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL14155864 | 0.65 | ALDH1A1 (0.54) | ALDH1A1ALOX15GAAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195556-B2 | Reversible protein multimers, methods for their production and use | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2025-01-14 | — | — | US | disclosed |
| US-20180346606-A1 | REVERSIBLE PROTEIN MULTIMERS, METHODS FOR THEIR PRODUCTION AND USE | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2018-12-06 | — | — | US | disclosed |
| US-10023657-B2 | Reversible protein multimers, methods for their production and use | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2018-07-17 | — | — | US | disclosed |
| US-20130289253-A1 | REVERSIBLE PROTEIN MULTIMERS, METHODS FOR THEIR PRODUCTION AND USE | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2013-10-31 | — | — | US | disclosed |
| WO-2012044999-A2 | REVERSIBLE PROTEIN MULTIMERS, METHODS FOR THEIR PRODUCTION AND USE | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180346606-A1 | REVERSIBLE PROTEIN MULTIMERS, METHODS FOR THEIR PRODUCTION AND USE | CD4, CD74, CD69 | ALDH1A1 4582/4885ALOX15 3919/4885GAA 3554/4885 |
| US-12195556-B2 | Reversible protein multimers, methods for their production and use | CD4, CD74, MICA | ALDH1A1 4777/4885ALOX15 4177/4885GAA 4226/4885 |
| US-20130289253-A1 | REVERSIBLE PROTEIN MULTIMERS, METHODS FOR THEIR PRODUCTION AND USE | CD4, CD74, CD69 | ALDH1A1 4582/4885ALOX15 3919/4885GAA 3554/4885 |
| US-10023657-B2 | Reversible protein multimers, methods for their production and use | CD4, CD74, CD69 | ALDH1A1 4582/4885ALOX15 3919/4885GAA 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.