Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28343039 | 0.78 | ALDH1A1 (0.56) | PKMALDH1A1HSP90AA1CCR6ATM | |
| SCHEMBL28755352 | 0.77 | TLR9 (0.45) | PKMKDM4EALDH1A1HSP90AA1CCR6 | |
| SCHEMBL4901236 | 0.74 | TLR9 (0.49) | PKMKDM4EALDH1A1HSP90AA1CCR6 | |
| SCHEMBL4432960 | 0.73 | PTPN1 (0.38) | PKMKDM4EALDH1A1TDP1GAA | |
| SCHEMBL3442183 | 0.71 | ALDH1A1 (0.41) | PKMKDM4EALDH1A1HSP90AA1CCR6 | |
| SCHEMBL896334 | 0.71 | ALDH1A1 (0.39) | PKMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL9479020 | 0.70 | MT-CO2 (0.50) | KDM4EALDH1A1TDP1GAAMAPT | |
| SCHEMBL7591474 | 0.68 | MGLL (0.49) | PKMALDH1A1HSP90AA1ATMNPSR1 | |
| SCHEMBL5495749 | 0.66 | — | — | |
| SCHEMBL79520 | 0.66 | KDM4E (0.36) | KDM4EALDH1A1ATMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077952-A1 | METHOD AND DEVICE FOR DETERMINING A NUCLEIC ACID ALLELE OR BASE SEQUENCE | CANON KABUSHIKI KAISHA (JP) | 2007-07-12 | — | — | WO | disclosed |