Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963972 | 0.89 | SLC6A4 (0.43) | SLC6A4SLC6A2TACR1SLC6A3CYP2D6 | |
| SCHEMBL8963846 | 0.88 | SLC6A4 (0.42) | SLC6A4SLC6A2TACR1SLC6A3CYP2D6 | |
| SCHEMBL8963882 | 0.84 | SLC6A4 (0.52) | SLC6A4SLC6A2TACR1SLC6A3PRMT5 | |
| Hydrochloric Acid SCHEMBL8963594 | 0.81 | DRD2 (0.36) | SLC6A4SLC6A2SLC6A3CYP2D6MEN1 | |
| SCHEMBL8963580 | 0.80 | PRMT5 (0.40) | SLC6A4SLC6A2TACR1MEN1KMT2A | |
| SCHEMBL8963825 | 0.79 | CYP3A4 (0.44) | SLC6A3CYP2D6KCNH2HRH3CYP2C9 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.79 | PRMT5 (0.40) | SLC6A4SLC6A2TACR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8963832 | 0.79 | SLC6A4 (0.35) | SLC6A4SLC6A2TACR1SLC6A3CYP2D6 | |
| SCHEMBL8963887 | 0.77 | CYP3A4 (0.46) | SLC6A3CYP2D6KCNH2MEN1KMT2A | |
| SCHEMBL8963679 | 0.74 | MEN1 (0.42) | SLC6A4SLC6A2MEN1KMT2APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |