Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963972 | 0.87 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3TACR1PRMT5 | |
| SCHEMBL8963464 | 0.84 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3TACR1PRMT5 | |
| SCHEMBL8963580 | 0.80 | PRMT5 (0.40) | SLC6A4SLC6A2TACR1PRMT5 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.79 | PRMT5 (0.40) | SLC6A4SLC6A2TACR1PRMT5 | |
| Hydrochloric Acid SCHEMBL8963832 | 0.77 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3TACR1PRMT5 | |
| SCHEMBL8963887 | 0.76 | CYP3A4 (0.46) | SLC6A3 | |
| SCHEMBL8963855 | 0.76 | TNKS (0.34) | SLC6A4SLC6A2TACR1PRMT5 | |
| SCHEMBL8964088 | 0.75 | OPRD1 (0.37) | PRMT5 | |
| SCHEMBL8963825 | 0.75 | CYP3A4 (0.44) | SLC6A3 | |
| Hydrochloric Acid SCHEMBL8963905 | 0.74 | PIN1 (0.36) | SLC6A4SLC6A2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |