Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.59 |
| ▸ | MMP12 | P39900 | 15/20 | 0.59 |
| ▸ | MMP9 | P14780 | 14/20 | 0.59 |
| ▸ | MMP8 | P22894 | 12/20 | 0.59 |
| ▸ | MMP13 | P45452 | 12/20 | 0.59 |
| ▸ | MMP14 | P50281 | 12/20 | 0.59 |
| ▸ | MMP16 | P51512 | 12/20 | 0.59 |
| ▸ | MMP3 | P08254 | 9/20 | 0.55 |
| ▸ | MMP1 | P03956 | 5/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609756 | 0.88 | MMP2 (0.58) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL19040679 | 0.84 | AKR1C3 (0.46) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL11610684 | 0.83 | MMP2 (0.55) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL29676384 | 0.83 | NPSR1 (0.47) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL34677 | 0.83 | NPSR1 (0.47) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL314725 | 0.83 | MMP2 (0.74) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL11699547 | 0.83 | FABP4 (0.45) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL11607950 | 0.81 | ALOX15 (0.44) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL11607020 | 0.80 | L3MBTL1 (0.66) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL11606623 | 0.79 | MMP2 (0.45) | MMP2MMP12MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |