SCHEMBL8964467

SCHEMBL8964467

Cc1ccc(S(=O)(=O)c2ccccc2C)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.60
HSD11B1 P28845 2/20 0.58
RAPGEF4 Q8WZA2 1/20 0.52
HTT P42858 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ABCC9 O60706 1/20 0.50
ABCC8 Q09428 1/20 0.50
KCNJ11 Q14654 1/20 0.50
KCNJ8 Q15842 1/20 0.50
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 2/20 0.49
NPSR1 Q6W5P4 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30893040 1.00 GAA (0.60) GAAHSD11B1RAPGEF4HTTSMN1; SMN2
SCHEMBL31000980 0.89 GAA (0.68) GAAHSD11B1RAPGEF4HTTSMN1; SMN2
SCHEMBL11853033 0.89 GAA (0.68) GAAHSD11B1RAPGEF4HTTSMN1; SMN2
SCHEMBL12336792 0.88 HTR6 (0.58) GAAHSD11B1HTTSMN1; SMN2ABCC9
SCHEMBL1713160 0.87 HTR6 (0.57) GAAHSD11B1HTTSMN1; SMN2ABCC9
SCHEMBL31092469 0.87 HTR6 (0.57) GAAHSD11B1HTTSMN1; SMN2ABCC9
(Phenylsulfonyl)Benzene SCHEMBL6332793 0.85 HTR6 (0.61) GAAHSD11B1HTTSMN1; SMN2ABCC9
SCHEMBL7635059 0.84 ALDH1A1 (0.56) GAAHSD11B1ABCC9ABCC8KCNJ11
SCHEMBL1585056 0.84 HSD11B1 (0.59) HSD11B1HTTABCC9ABCC8KCNJ11
SCHEMBL6001994 0.84 HTR6 (0.59) GAAHSD11B1ABCC9ABCC8KCNJ11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924279-A MELK inhibitor and application thereof 中山大学 2024-04-26 CN claimed
CN-120092035-A Cationically curable composition 日产化学株式会社 2025-06-03 CN disclosed
CN-117924279-B MELK inhibitor and application thereof 中山大学 2024-07-16 CN disclosed
CN-117924279-A MELK inhibitor and application thereof 中山大学 2024-04-26 CN disclosed
CN-117916290-A Ultraviolet-curable resin composition, adhesive, sealant, insulation protective agent, and electronic circuit board 荒川化学工业株式会社 2024-04-19 CN disclosed
CN-117886723-A Synthesis method of 2-chloro-4-methylsulfonyl benzoic acid 辽宁龙田化工科技有限公司 2024-04-16 CN disclosed
CN-117263832-A Synthesis method of 2-chloro-4-methylsulfonyl benzoic acid 辽宁龙田化工科技有限公司 2023-12-22 CN disclosed
US-20230242681-A1 POLYMERIZATION INITIATOR, KIT FOR PREPARING CURABLE COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2023-08-03 US disclosed
CN-109535046-B Preparation method of sulfoxide compound 江南大学 2020-01-17 CN disclosed
CN-108623503-B Green preparation method of vinyl sulfone derivative in water phase 宁波大学 2020-01-03 CN disclosed
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-20130222720-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE KONICA MINOLTA , INC. (JP) 2013-08-29 US disclosed
US-20130222720-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE KONICA MINOLTA , INC. (JP) 2013-08-29 US disclosed
US-7751005-B2 Liquid crystal display apparatus KONICA MINOLTA OPTO, INC. (JP) 2010-07-06 US disclosed
US-7751005-B2 Liquid crystal display apparatus KONICA MINOLTA OPTO, INC. (JP) 2010-07-06 US disclosed
US-20080084523-A1 LIQUID CRYSTAL DISPLAY APPARATUS KONICA MINOLTA OPTO, INC. (JP) 2008-04-10 US disclosed
US-20080084523-A1 LIQUID CRYSTAL DISPLAY APPARATUS KONICA MINOLTA OPTO, INC. (JP) 2008-04-10 US disclosed
EP-0693094-A1 HIGH IMPACT POLYESTER/POLYCARBONATE BLENDS AlliedSignal Inc. (US) 1996-01-24 EP disclosed
WO-1994022955-A1 HIGH IMPACT POLYESTER/POLYCARBONATE BLENDS ALLIEDSIGNAL INC. (US) 1994-10-13 WO disclosed
US-5283285-A Comprising an amine functionalized elastomer, a graft coupling agent; molding materials for sport, technical, household equipement; heat and chemical resistance ALLIEDSIGNAL INC. (US) 1994-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242681-A1 POLYMERIZATION INITIATOR, KIT FOR PREPARING CURABLE COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL KIT, SETDB1, NOD1 GAA 3302/4885HSD11B1 4702/4885RAPGEF4 2378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.