SCHEMBL8964597

SCHEMBL8964597

C=C(Cl)Cc1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.50
CAMK2A Q9UQM7 1/20 0.50
ESR1 P03372 3/20 0.48
ESR2 Q92731 3/20 0.48
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45
ABAT P80404 1/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
SLC6A2 P23975 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTR3A P46098 1/20 0.41
BACE1 P56817 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
IDO1 P14902 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10546280 0.80 LMNA (0.31) CA2CAMK2AALDH1A1LMNA
SCHEMBL10546832 0.80 TSHR (0.42) CA2CAMK2AALDH1A1CA12CA1
SCHEMBL9774960 0.80 LMNA (0.47) NPC1RAB9AALDH1A1TAAR1L3MBTL1
Anolignan B SCHEMBL23268876 0.79 CA2 (0.54) CA2CAMK2AESR1ESR2FNTA
SCHEMBL3899223 0.78 RAB9A (0.46) NPC1RAB9AALDH1A1TAAR1L3MBTL1
SCHEMBL7856390 0.77 CA2 (0.58) CA2CAMK2AESR1ESR2FNTA
SCHEMBL3113565 0.77 CES1 (0.50) FNTAFNTBALDH1A1CYP2C19L3MBTL1
SCHEMBL8964346 0.77 CA2 (0.52) CA2CAMK2AESR1ESR2FNTA
SCHEMBL7735456 0.77 CA2 (0.52) CA2CAMK2AESR1ESR2FNTA
SCHEMBL465583 0.75 CA2 (0.50) CA2CAMK2AESR1ESR2FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118874435-A Preparation method of macroporous adsorption resin for waste gas treatment 蚌埠市天星树脂有限责任公司 2024-11-01 CN claimed
CN-118874435-A Preparation method of macroporous adsorption resin for waste gas treatment 蚌埠市天星树脂有限责任公司 2024-11-01 CN disclosed
CN-118874435-A Preparation method of macroporous adsorption resin for waste gas treatment 蚌埠市天星树脂有限责任公司 2024-11-01 CN disclosed
EP-0410379-B1 Pharmaceutically active 3-aryl and 3-heteroaryl-2-fluoro-1-olefins MERRELL DOW PHARMA (US) 1996-01-31 EP disclosed
US-5068465-A Hypotensive agents or enzyme inhibitors for treatment of hypertension MERRELL DOW PHARMACEUTICALS INC. (US) 1991-11-26 US disclosed
EP-0410379-A2 Pharmaceutically active 3-aryl and 3-heteroaryl-2-fluoro-1-olefins MERRELL DOW PHARMACEUTICALS INC. (US) 1991-01-30 EP disclosed
US-4981868-A ENZYME INHIBITORS, HYPOTENSIVES MERRELL DOW PHARMACEUTICAL (US) 1991-01-01 US disclosed