SCHEMBL3899223

SCHEMBL3899223

C=C(Cl)Cc1ccc(C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CTBP2 P56545 1/20 0.42
IDO1 P14902 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HPGD P15428 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
CNR2 P34972 1/20 0.39
ACHE P22303 1/20 0.38
AGXT P21549 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
FAAH O00519 1/20 0.38
MGLL Q99685 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8964597 0.78 CA2 (0.50) RAB9ANPC1L3MBTL1CTBP2IDO1
SCHEMBL20618816 0.78 IDO1 (0.44) RAB9ANPC1L3MBTL1CTBP2IDO1
SCHEMBL9774960 0.78 LMNA (0.47) RAB9ANPC1L3MBTL1CTBP2IDO1
SCHEMBL10546280 0.78 LMNA (0.31) ALDH1A1
SCHEMBL10546832 0.78 TSHR (0.42) ALDH1A1
SCHEMBL3899314 0.78 IDO1 (0.44) RAB9ANPC1L3MBTL1CTBP2IDO1
SCHEMBL18772414 0.77 HPGD (0.46) RAB9ANPC1L3MBTL1CTBP2IDO1
SCHEMBL24386036 0.76 IDO1 (0.47) RAB9ANPC1L3MBTL1CTBP2IDO1
SCHEMBL657538 0.76 RAB9A (0.55) RAB9ANPC1L3MBTL1CTBP2ALDH1A1
SCHEMBL2407618 0.76 ALDH1A1 (0.46) RAB9ANPC1L3MBTL1CTBP2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4344906-A VINYLAROMATIC, MALEIC ANHYDRIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-08-17 US claimed
EP-1445084-B1 A method of forming a decorative glass/resin laminate GROUP FOUR GLASSFIBRE CO LTD (GB) 2009-03-18 EP disclosed
US-20040159975-A1 Method of forming a decorative structure and a decorative structure made by the method GROUP FOUR GLASSFIBRE CO. LIMITED (GB) 2004-08-19 US disclosed
EP-1445084-A1 A method of forming a decorative glass/resin laminate and laminate made by the method Creative Plastics International Limited (GB) 2004-08-11 EP disclosed
US-4344906-A VINYLAROMATIC, MALEIC ANHYDRIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-08-17 US disclosed