Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4591818 | 0.89 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1ABCB1MEN1 | |
| SCHEMBL17670218 | 0.84 | TDP1 (0.50) | ALDH1A1TDP1L3MBTL1ABCB1MEN1 | |
| SCHEMBL5068702 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TDP1MEN1POLBMAPT | |
| SCHEMBL4103425 | 0.79 | MAPT (0.49) | ALDH1A1TDP1L3MBTL1MEN1POLB | |
| SCHEMBL5069290 | 0.78 | TDP1 (0.51) | ALDH1A1TDP1MEN1POLBMAPT | |
| SCHEMBL32662713 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TDP1MEN1POLBMAPT | |
| SCHEMBL28827487 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TDP1MEN1MAPTKMT2A | |
| SCHEMBL15461976 | 0.78 | ALDH1A1 (0.69) | ALDH1A1TDP1MEN1POLBMAPT | |
| SCHEMBL8502642 | 0.77 | PGR (0.49) | ALDH1A1POLBMAPTCYP3A4TSHR | |
| SCHEMBL22007056 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TDP1MEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |