Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964855 | 0.84 | NPC1 (0.44) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28615254 | 0.84 | TMPRSS15 (0.33) | EGFRRETMAPK14RAF1MAPK11 | |
| SCHEMBL9566966 | 0.83 | EGFR (0.46) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6632393 | 0.77 | TMPRSS15 (0.55) | EGFRNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL12647131 | 0.76 | MEN1 (0.43) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1515627 | 0.74 | ALDH1A1 (0.49) | EGFRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28468084 | 0.74 | MEN1 (0.55) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL803439 | 0.74 | MEN1 (0.44) | EGFRNPC1RAB9AMEN1KMT2A | |
| Carbamic Acid Phenyl Ester SCHEMBL769687 | 0.73 | RAF1 (0.47) | NPC1RAB9AMEN1KMT2AMAPK14 | |
| Hydrochloric Acid SCHEMBL3712256 | 0.73 | ALDH1A1 (0.48) | EGFRNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105936-A | Imidazo [1,2-a ] pyridine compound serving as FLT3 inhibitor, and preparation method and application thereof | 遵义医科大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-116075513-A | Inhibitors of NEK7 kinase | 哈利亚治疗公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115843272-A | Inhibitors of NEK7 kinase | 哈利亚治疗公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-111606887-B | Novel kinase inhibitor | 安徽中科拓苒药物科学研究有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-113354630-B | 5,6-dihydrobenzo [ h ] quinazoline compound and application thereof | 江南大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113354630-A | 5, 6-dihydrobenzo [ h ] quinazoline compound and application thereof | 江南大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-109641893-B | Novel imidazopyridine derivatives, process for their preparation and their use | 大邱庆北尖端医疗产业振兴财团 | 2021-07-20 | — | — | CN | disclosed |
| CN-111606887-A | Novel kinase inhibitor | 安徽中科拓苒药物科学研究有限公司 | 2020-09-01 | — | — | CN | disclosed |
| CN-105461709-B | Substituted urea derivatives and their use in medicine | 广东东阳光药业有限公司 | 2020-01-21 | — | — | CN | disclosed |
| WO-2015043492-A1 | SUBSTITUTED UREA DERIVATIVES AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-04-02 | — | — | WO | disclosed |
| EP-0459244-B1 | Sulphonilised carboxylic acid amides | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0569810-A1 | Sulphonylamide herbicides | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |
| EP-0459244-A1 | Sulphonilised carboxylic acid amides | BAYER AG (DE) | 1991-12-04 | — | — | EP | disclosed |