SCHEMBL6632393

SCHEMBL6632393

Cc1cc(OC(N)=O)no1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TMPRSS15 P98073 1/20 0.55
POLB P06746 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 10/20 0.40
NPC1 O15118 8/20 0.40
ALDH1A1 P00352 4/20 0.40
TP53 P04637 1/20 0.40
GLA P06280 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
EGFR P00533 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.38
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM3 P20309 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875579 0.82 TMPRSS15 (0.49) TMPRSS15L3MBTL1MAPTRAB9ANPC1
SCHEMBL27361867 0.82 RAB9A (0.49) TMPRSS15L3MBTL1MAPTRAB9ANPC1
SCHEMBL8305554 0.81 TMPRSS15 (0.48) TMPRSS15L3MBTL1MAPTRAB9ANPC1
SCHEMBL9844093 0.79 TMPRSS15 (0.47) TMPRSS15L3MBTL1MAPTRAB9ANPC1
SCHEMBL23723952 0.79 TMPRSS15 (0.47) TMPRSS15POLBL3MBTL1MAPTRAB9A
SCHEMBL19520914 0.78 TMPRSS15 (0.49) TMPRSS15L3MBTL1MAPTRAB9ANPC1
SCHEMBL8964871 0.77 EGFR (0.43) POLBL3MBTL1MAPTRAB9ANPC1
SCHEMBL22723991 0.77 L3MBTL1 (0.55) TMPRSS15POLBL3MBTL1MAPTRAB9A
SCHEMBL27952188 0.77 TMPRSS15 (0.45) TMPRSS15L3MBTL1MAPTRAB9ANPC1
SCHEMBL29138450 0.75 SMN1; SMN2 (0.47) TMPRSS15POLBL3MBTL1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4654968-A1 PROCESS FOR THE PREPARATION OF TIVOZANIB OR A SALT THEREOF Alivus Life Sciences Limited (IN) 2025-12-03 EP claimed
WO-2024157170-A1 PROCESS FOR THE PREPARATION OF TIVOZANIB OR A SALT THEREOF GLENMARK LIFE SCIENCES LIMITED (IN) 2024-08-02 WO claimed
EP-0829470-B1 2-Cyano-3,5-dihydroxy-hex-2-ene carboxamide derivatives, process for their preparation and their use as medicaments HOECHST AG (DE) 1999-12-15 EP claimed
EP-0829470-A1 2-Cyano-3,5-dihydroxy-hex-2-ene carboxamide derivatives, process for their preparation and their use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1998-03-18 EP claimed
EP-4654968-A1 PROCESS FOR THE PREPARATION OF TIVOZANIB OR A SALT THEREOF Alivus Life Sciences Limited (IN) 2025-12-03 EP disclosed
WO-2024157170-A1 PROCESS FOR THE PREPARATION OF TIVOZANIB OR A SALT THEREOF GLENMARK LIFE SCIENCES LIMITED (IN) 2024-08-02 WO disclosed
CN-117105936-A Imidazo [1,2-a ] pyridine compound serving as FLT3 inhibitor, and preparation method and application thereof 遵义医科大学 2023-11-24 CN disclosed
CN-115843272-A Inhibitors of NEK7 kinase 哈利亚治疗公司 2023-03-24 CN disclosed
CN-113354630-B 5,6-dihydrobenzo [ h ] quinazoline compound and application thereof 江南大学 2022-11-01 CN disclosed
CN-113354630-A 5, 6-dihydrobenzo [ h ] quinazoline compound and application thereof 江南大学 2021-09-07 CN disclosed
CN-111362972-B Benzimidazole [2,1-b ] thiazole compound and application thereof 江南大学 2021-08-24 CN disclosed
CN-108349963-B Sodium channel blockers 株式会社大熊制药 2021-03-30 CN disclosed
CN-111362972-A Benzimidazole [2,1-b ] thiazole compound and application thereof 江南大学 2020-07-03 CN disclosed
WO-2014111871-A1 4,5-DIHYDROISOXAZOLE DERIVATIVES AS NAMPT INHIBITORS AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2014-07-24 WO disclosed
EP-1458374-A2 COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2004-09-22 EP disclosed
WO-2003051841-A2 COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed
EP-0829470-B1 2-Cyano-3,5-dihydroxy-hex-2-ene carboxamide derivatives, process for their preparation and their use as medicaments HOECHST AG (DE) 1999-12-15 EP disclosed
EP-0829470-A1 2-Cyano-3,5-dihydroxy-hex-2-ene carboxamide derivatives, process for their preparation and their use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1998-03-18 EP disclosed