Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964855 | 0.84 | NPC1 (0.44) | EGFRALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL8964871 | 0.83 | EGFR (0.43) | EGFRALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL8305554 | 0.77 | TMPRSS15 (0.48) | EGFRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9315098 | 0.74 | ALDH1A1 (0.53) | EGFRALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL803439 | 0.74 | MEN1 (0.44) | EGFRALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL19454702 | 0.72 | MEN1 (0.43) | EGFRALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL12647131 | 0.72 | MEN1 (0.43) | EGFRALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL6650653 | 0.70 | ALDH1A1 (0.58) | EGFRALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL11158107 | 0.70 | EGFR (0.69) | EGFRNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL26151601 | 0.70 | MEN1 (0.39) | EGFRALDH1A1MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551821-A1 | Isoxazolecarboxylic acid derivatives and their use as herbicides | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |