Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964905 | 0.88 | CYP17A1 (0.48) | MEN1KMT2ANFE2L2PTGS1ALOX5 | |
| SCHEMBL8965561 | 0.88 | BCL2L1 (0.48) | MEN1KMT2ANFE2L2LMNAHPGD | |
| SCHEMBL8965558 | 0.88 | BCL2L1 (0.48) | MEN1KMT2ANFE2L2LMNAHPGD | |
| SCHEMBL8964910 | 0.88 | CYP17A1 (0.48) | MEN1KMT2ANFE2L2PTGS1ALOX5 | |
| SCHEMBL8965132 | 0.88 | BCL2L1 (0.48) | MEN1KMT2ANFE2L2LMNAHPGD | |
| SCHEMBL8964911 | 0.88 | CYP17A1 (0.48) | MEN1KMT2ANFE2L2PTGS1ALOX5 | |
| SCHEMBL8964908 | 0.88 | CYP17A1 (0.48) | MEN1KMT2ANFE2L2PTGS1ALOX5 | |
| SCHEMBL8965199 | 0.76 | NFE2L2 (0.46) | NFE2L2PTGS1PTGS2 | |
| SCHEMBL9516689 | 0.75 | ALOX5 (0.62) | MEN1KMT2ANFE2L2LMNAHPGD | |
| SCHEMBL9516692 | 0.75 | ALOX5 (0.62) | MEN1KMT2ANFE2L2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696271-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025430-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |