SCHEMBL8965267

SCHEMBL8965267

COc1ccc(/C=C/C(=O)c2ccc(O)cc2)c([N+](=O)[O-])c1Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 5/20 0.55
CTSB P07858 5/20 0.55
CAPN1 P07384 3/20 0.55
MAOB P27338 1/20 0.54
TDP1 Q9NUW8 1/20 0.51
PTPN1 P18031 2/20 0.46
MAPT P10636 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
LMNA P02545 1/20 0.46
BCHE P06276 1/20 0.46
DPP4 P27487 3/20 0.45
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ABCG2 Q9UNQ0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965265 1.00 CTSL (0.55) CTSLCTSBCAPN1MAOBTDP1
SCHEMBL8965121 0.89 NPC1 (0.43) CTSLCTSBCAPN1MAOBMAPT
SCHEMBL8977026 0.84 MAPT (0.53) CTSLCAPN1MAOBTDP1MAPT
SCHEMBL8977029 0.84 MAPT (0.53) CTSLCAPN1MAOBTDP1MAPT
SCHEMBL8964956 0.71 MAOB (1.00) CTSLCTSBCAPN1MAOBTDP1
SCHEMBL29403206 0.71 MAOB (1.00) CTSLCTSBCAPN1MAOBTDP1
SCHEMBL8964952 0.71 MAOB (1.00) CTSLCTSBCAPN1MAOBTDP1
SCHEMBL7188238 0.70 LMNA (0.55) MAOBTDP1MAPTNPC1RAB9A
SCHEMBL7188233 0.70 LMNA (0.55) MAOBTDP1MAPTNPC1RAB9A
SCHEMBL5517453 0.70 MAOB (0.67) CTSLCAPN1MAOBTDP1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US disclosed