Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.39 |
| ▸ | RBP1 | P09455 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358333 | 0.85 | MEN1 (0.45) | PKMPOLBMEN1KMT2AMAPK1 | |
| SCHEMBL8965280 | 0.84 | PTGDR2 (0.55) | PKMPOLBMEN1KMT2APTGDR2 | |
| SCHEMBL8965331 | 0.82 | PTGDR2 (0.39) | KMT2APTGDR2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL1789805 | 0.72 | PPARA (0.56) | MTNR1AMTNR1BACHE | |
| SCHEMBL28337010 | 0.71 | PPARA (0.62) | MTNR1AMTNR1BACHE | |
| SCHEMBL31539531 | 0.70 | CYP4F2 (0.54) | MTNR1AMTNR1BACHE | |
| SCHEMBL8413677 | 0.69 | PTGIR (0.46) | PKMPOLBRBP1LMNAALDH1A1 | |
| SCHEMBL28593564 | 0.69 | ACHE (0.58) | KMT2AMTNR1AMTNR1BACHE | |
| SCHEMBL11206161 | 0.69 | ACHE (0.51) | MTNR1AMTNR1BACHE | |
| SCHEMBL27564217 | 0.68 | ACHE (0.56) | MEN1KMT2AMTNR1AMTNR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |