Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965352 | 0.99 | ALOX5 (0.51) | ALOX5LMNAMEN1NPC1HTT | |
| SCHEMBL8967160 | 0.88 | ALOX5 (0.48) | ALOX5LMNAMEN1NPC1HTT | |
| SCHEMBL8965298 | 0.80 | ALOX5 (0.60) | ALOX5HDAC6FFAR1 | |
| SCHEMBL8801377 | 0.80 | ALOX5 (0.50) | ALOX5LMNAMEN1NPC1HTT | |
| SCHEMBL8800737 | 0.79 | ALOX5 (0.51) | ALOX5LMNAMEN1NPC1HTT | |
| SCHEMBL8965945 | 0.70 | ALOX5 (0.54) | ALOX5HDAC6 | |
| SCHEMBL8800021 | 0.70 | ALOX5 (0.58) | ALOX5HDAC6MMP13MMP14 | |
| SCHEMBL8799350 | 0.69 | ALOX5 (0.60) | ALOX5HDAC6 | |
| SCHEMBL8799902 | 0.68 | ALOX5 (0.53) | ALOX5HDAC6MMP13MMP14 | |
| SCHEMBL8800909 | 0.68 | ALOX5 (0.58) | ALOX5MEN1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |