Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801596 | 0.79 | PDE10A (0.53) | CYSLTR1GPBAR1ALOX5APALOX5HDAC6 | |
| SCHEMBL9493090 | 0.78 | ALOX5 (0.50) | CYSLTR1GPBAR1ALOX5HDAC6 | |
| SCHEMBL9492165 | 0.77 | CYSLTR1 (0.51) | CYSLTR1GPBAR1ALOX5APALOX5HDAC6 | |
| SCHEMBL9490780 | 0.77 | CYSLTR1 (0.50) | CYSLTR1GPBAR1ALOX5APALOX5HDAC6 | |
| SCHEMBL8801993 | 0.75 | PDE10A (0.51) | CYSLTR1GPBAR1ALOX5APALOX5HDAC6 | |
| SCHEMBL9598096 | 0.73 | ALOX5 (0.52) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL10682896 | 0.73 | ALOX5AP (0.54) | CYSLTR1GPBAR1ALOX5APALOX5HDAC6 | |
| SCHEMBL10587917 | 0.70 | CYSLTR1 (0.57) | CYSLTR1GPBAR1ALOX5APCYSLTR2 | |
| SCHEMBL8964963 | 0.70 | ALOX5 (0.67) | ALOX5HDAC6 | |
| Hydroxyamine SCHEMBL8967003 | 0.70 | CYSLTR1 (0.43) | CYSLTR1GPBAR1ALOX5APALOX5CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |