Sugi Predict

Sugi Predict / Compounds / Hydroxyamine

Hydroxyamine

Hydroxyamine

SCHEMBL8967003

C1=c2c(on2C2CCCc3cc(OCc4ccc5ccccc5n4)ccc32)=N1.NO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CYSLTR1 Q9Y271 7/20 0.43
▸ GPBAR1 Q8TDU6 5/20 0.43
▸ CYSLTR2 Q9NS75 3/20 0.43
▸ ALOX5AP P20292 1/20 0.41
▸ ALOX5 P09917 1/20 0.41
▸ PDE10A Q9Y233 2/20 0.41
▸ CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8801596 0.77 PDE10A (0.53) CYSLTR1GPBAR1CYSLTR2ALOX5APALOX5
SCHEMBL8801993 0.75 PDE10A (0.51) CYSLTR1GPBAR1CYSLTR2ALOX5APALOX5
SCHEMBL9490780 0.74 CYSLTR1 (0.50) CYSLTR1GPBAR1CYSLTR2ALOX5APALOX5
SCHEMBL9492165 0.73 CYSLTR1 (0.51) CYSLTR1GPBAR1CYSLTR2ALOX5APALOX5
SCHEMBL9493090 0.72 ALOX5 (0.50) CYSLTR1GPBAR1ALOX5
SCHEMBL10682896 0.71 ALOX5AP (0.54) CYSLTR1GPBAR1CYSLTR2ALOX5APALOX5
Hydroxyamine SCHEMBL8801706 0.71 ALOX5 (0.57) ALOX5
SCHEMBL8965369 0.70 CYSLTR1 (0.49) CYSLTR1GPBAR1CYSLTR2ALOX5APALOX5
SCHEMBL9598096 0.68 ALOX5 (0.52) CYSLTR1GPBAR1CYSLTR2ALOX5
SCHEMBL7092609 0.67 CYSLTR1 (0.76) CYSLTR1GPBAR1CYSLTR2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5512581-A ANTIINFLAMMATORY AGENT ABBOTT LABORATORIES (US) 1996-04-30 — — US disclosed