SCHEMBL8965383

SCHEMBL8965383

CC(C)C(C)C[N+]1(Cc2ccccc2)CCOCC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.36
APOBEC3A P31941 2/20 0.35
APOBEC3G Q9HC16 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2D6 P10635 3/20 0.34
MEN1 O00255 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KMT2A Q03164 2/20 0.34
KCNA5 P22460 1/20 0.34
USP2 O75604 1/20 0.34
PLA2G1B P04054 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
SIGMAR1 Q99720 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965936 0.87 TRPA1 (0.38) TRPA1APOBEC3AAPOBEC3GCYP2D6CHRNB4
SCHEMBL8965229 0.85 PABPC1 (0.37) TRPA1APOBEC3AAPOBEC3GCYP2D6CHRNB4
SCHEMBL8965989 0.85 PABPC1 (0.37) TRPA1APOBEC3AAPOBEC3GCYP2D6CHRNB4
SCHEMBL8056810 0.80 CHRNA7 (0.44) APOBEC3AAPOBEC3GSMN1; SMN2CYP2D6MEN1
SCHEMBL6122174 0.77 SMN1; SMN2 (0.36) APOBEC3AAPOBEC3GSMN1; SMN2CYP2D6MEN1
SCHEMBL8965317 0.74 APOBEC3A (0.36) APOBEC3AAPOBEC3GSMN1; SMN2CYP2D6MEN1
SCHEMBL8965744 0.74 ALDH1A1 (0.37) APOBEC3AAPOBEC3GSMN1; SMN2CYP2D6MEN1
Water SCHEMBL1702603 0.72 SMN1; SMN2 (0.44) APOBEC3AAPOBEC3GSMN1; SMN2CYP2D6MEN1
SCHEMBL8053841 0.72 DNM1 (0.37) APOBEC3AAPOBEC3GSMN1; SMN2CYP2D6MEN1
SCHEMBL7723410 0.72 DNM1 (0.37) APOBEC3AAPOBEC3GSMN1; SMN2CYP2D6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0619300-B1 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF AG (DE) 1996-12-27 EP disclosed
US-5510528-A Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
US-5446199-A Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1995-08-29 US disclosed
EP-0619300-A2 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF Aktiengesellschaft (DE) 1994-10-12 EP disclosed