SCHEMBL8966039

SCHEMBL8966039

CCOCC(C)C[N+]1(Cc2ccccc2)CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
PABPC1 P11940 2/20 0.35
APOBEC3A P31941 2/20 0.35
APOBEC3G Q9HC16 2/20 0.35
EIF4H Q15056 1/20 0.35
TSHR P16473 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32
OPRL1 P41146 1/20 0.32
CYP2D6 P10635 2/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC22A2 O15244 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965696 0.84 NPC1 (0.37) NPC1RAB9APABPC1APOBEC3AAPOBEC3G
SCHEMBL8965111 0.81 NPC1 (0.38) NPC1RAB9APABPC1APOBEC3AAPOBEC3G
SCHEMBL8965334 0.81 NPC1 (0.38) NPC1RAB9APABPC1APOBEC3AAPOBEC3G
SCHEMBL8054698 0.79 PABPC1 (0.39) NPC1RAB9APABPC1APOBEC3AAPOBEC3G
SCHEMBL8965910 0.77 CYP2D6 (0.36) NPC1RAB9APABPC1APOBEC3AAPOBEC3G
SCHEMBL8965968 0.77 CYP2D6 (0.36) NPC1RAB9APABPC1APOBEC3AAPOBEC3G
SCHEMBL8965229 0.76 PABPC1 (0.37) NPC1RAB9APABPC1APOBEC3AAPOBEC3G
SCHEMBL8965989 0.76 PABPC1 (0.37) NPC1RAB9APABPC1APOBEC3AAPOBEC3G
SCHEMBL8965936 0.74 TRPA1 (0.38) NPC1RAB9APABPC1APOBEC3AAPOBEC3G
SCHEMBL5944660 0.73 CHRNA7 (0.43) NPC1RAB9APABPC1APOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0619300-B1 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF AG (DE) 1996-12-27 EP disclosed
US-5510528-A Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
US-5446199-A Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1995-08-29 US disclosed
EP-0619300-A2 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF Aktiengesellschaft (DE) 1994-10-12 EP disclosed