Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966102 | 1.00 | ANPEP (0.49) | ANPEPRNPEPDNPEPLTA4HCA12 | |
| SCHEMBL5492848 | 0.85 | LTA4H (0.50) | ANPEPRNPEPDNPEPLTA4HCA12 | |
| SCHEMBL11201637 | 0.83 | MMP1 (0.45) | ANPEPRNPEPDNPEPLTA4HCA12 | |
| SCHEMBL10443784 | 0.81 | SLC15A1 (0.46) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL28221965 | 0.80 | ANPEP (0.47) | ANPEPRNPEPDNPEPLTA4HCA12 | |
| SCHEMBL28786062 | 0.80 | ANPEP (0.55) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL28786054 | 0.80 | ANPEP (0.55) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL6250435 | 0.79 | SLC7A5 (0.47) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL27802016 | 0.79 | ANPEP (0.49) | ANPEPRNPEPDNPEPLTA4HALPI | |
| Phenylalanine Methyl Ester SCHEMBL6748761 | 0.79 | SLC7A5 (0.58) | ANPEPRNPEPDNPEPLTA4HCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593557-B1 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME (GB) | 1996-01-31 | — | — | EP | disclosed |
| EP-0593557-A1 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY. | MERCK SHARP & DOHME (GB) | 1994-04-27 | — | — | EP | disclosed |